Abstract

The COVID-19 pandemic has affected the world population across the globe. India has the second largest number of cases and the third largest number of deaths due to COVID-19 in the world. There have been close to 4.4 lakh deaths due to COVID-19 in India alone. The second wave in India has led to devastating consequences, particularly among the young population. The initial clinical symptoms of COVID-19 are similar to all types of viral pneumonia, with varying degrees of severity. The cases’ clinical manifestations include fever, nonproductive cough, dyspnea, myalgia, and fatigue. This study was undertaken with the purpose of identifying the relationship between the symptoms and duration in COVID-19-affected patients. The common presenting symptoms were fever (44.5%), sore throat (38.7%), and cough (36.12%). Most of the cases presented with a combination of fever with cough (35%) and fever with sore throat (33%). The duration of symptoms varied from one to 17 days with a mean of 5.75 days. Despite vaccination being started, the risk of the imminent third wave in the country is existential. Mutations in the coronavirus pose a threat to the vulnerable population. It is important to identify the combination of symptoms most predictive of COVID-19 to help guide recommendations for self-isolation, testing, and preventing further spread of the disease. Further studies using these models can yield better results in surveillance and containing this infectious disease.

Highlights

  • The COVID-19 pandemic has affected the world population across the globe

  • It is important to identify the combination of symptoms most predictive of COVID-19 to help guide recommendations for self-isolation, testing, and preventing further spread of the disease

  • All those who presented to the screening outpatient department (OPD) from May 2020 were assessed according to the Indian Council of Medical Research (ICMR) guidelines for testing for COVID19 [11,12]

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Summary

Introduction

The COVID-19 pandemic has affected the world population across the globe. The first coronavirus case was reported in India on January 30, 2020, in the state of Kerala. The second wave in India has led to devastating consequences, among the young population. Studies have identified various circulating double mutant and triple mutant strains of SARS-CoV-2 across different regions of India, which are more pathogenic than the initial strains. Such altered transmissibility and pathogenicity indicate the evolution of the virus [2]. India launched its vaccine drive against COVID-19 on January 16, 2021, mostly relying on Covishield, a version of the OxfordAstraZeneca vaccine produced by the Serum Institute of India [4]

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