Abstract
Purpose We determined the need for urological screening in children with neurofibromatosis. Materials and Methods Of 96 children with neurofibromatosis treated at our institution 6 (6.2 percent) had a symptomatic tumor that affected the urinary tract. Results There were 5 plexiform neurofibromas and 1 prostatic rhabdomvosarcoma. Five children had a palpable abdominal mass and 3 required urinary diversion. Conclusions Since most morbidity resulted because tumors were advanced by the time symptoms developed, we suggest that children with neurofibromatosis be screened annually with medical history, physical examination, urinalysis and serum chemistry studies for tumors that affect the urinary tract.
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