Symptomatic osteomalacia secondary to clinically occult causes.

Abstract

Case Reports1 June 1961SYMPTOMATIC OSTEOMALACIA SECONDARY TO CLINICALLY OCCULT CAUSESRICHARD C. POWELL, M.D., WILLIAM P. DEISS JR., M.D., F.A.C.P.RICHARD C. POWELL, M.D.Search for more papers by this author, WILLIAM P. DEISS JR., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-6-1280 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe purpose of this report is to describe two adult patients with disabling osteomalacia. The feature worthy of emphasis in each case is the negligible symptomatology referable to the organ systems believed to be the sites of the primary defects—in the first case, the gastrointestinal tract with occult steatorrhea; in the second, the kidneys with latent tubular acidosis.CASE REPORTSCase 1. A 50-year-old housewife was first seen by us in February, 1959, complaining of stiffness and generalized aching pain in her back and both lower extremities. The pain was not well localized. The onset of symptoms was insidious, and...Bibliography1. Milkman LA: Multiple spontaneous idiopathic symmetrical fractures. Amer. J. Roentgenol. 32: 622, 1934. Google Scholar2. AlbrightReifenstein FEC: The parathyroid glands and metabolic bone disease: selected studies. The Williams and Wilkins Company, Baltimore. 1948. Google Scholar3. CameronBensleyWood DGEHP: Latent steatorrhea. Ann. Intern. Med. 37: 553, 1952. LinkGoogle Scholar4. JuergensScholzWollaeger JSDAEE: Severe osteomalacia associated with occult steatorrhea due to nontropical sprue: report of five cases. Arch. Intern. Med. 98: 774, 1956. CrossrefGoogle Scholar5. Mudge GH: Clinical patterns of tubular dysfunction. Amer. J. Med. 24: 785, 1958. CrossrefMedlineGoogle Scholar6. FossPerryWood GLCBFJ: Renal tubular acidosis. Quart. J. Med. 25: 18, 1956. Google Scholar7. SchreinerSmithKyle GELHLH: Renal hyperchloremic acidosis: familial occurrence of nephrocalcinosis with hyperchloremia and low serum bicarbonate. Amer. J. Med. 15: 122, 1953. CrossrefMedlineGoogle Scholar8. AlbrightBurnettParsonReifensteinRoos FCHWECA: Osteomalacia and late rickets. Medicine 25: 399, 1946. CrossrefMedlineGoogle Scholar9. MilneStanburyThomson MDSWAE: Observations on the Fanconi syndrome and renal hyperchloraemic acidosis in the adult. Quart. J. Med. 21: 61, 1952. MedlineGoogle Scholar10. JacksonLinder WPGC: Innate functional defects of the renal tubules, with particular reference to the Fanconi syndrome: cases with retinitis pigmentosa. Quart. J. Med. 22: 133, 1953. MedlineGoogle Scholar11. JacksonDowdleLinder WPEGC: Vitamin D-resistant osteomalacia. Brit. Med. J. 1: 1269, 1958. CrossrefMedlineGoogle Scholar12. Reynolds TB: Observations on the pathogenesis of renal tubular acidosis. Amer. J. Med. 25: 503, 1958. CrossrefMedlineGoogle Scholar13. ElkintonHuthClarkBarkerSeligson JREJJKESD: Renal tubular acidosis with organic aciduria during paraldehyde ingestion: six-year study of an unusual case. Amer. J. Med. 23: 977, 1957. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, Indiana*Received for publication September 14, 1959.From the Department of Medicine, Indiana University School of Medicine.Requests for reprints should be addressed to Richard C. Powell, M.D., Department of Medicine, Indiana University School of Medicine, Indianapolis 7, Ind. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDisabling osteomalacic myopathy as the only presenting feature of coeliac diseaseA patient with osteomalacia as single presenting symptom of gluten-sensitive enteropathyDas PeritoneumDie intestinale Calcium-Resorption und ihre St�rungenDie erworbenen, generalisierten OsteopathienCalcium Absorption in Health and DiseaseRecent Progress in Osteomalacia and RicketsA. ROBERT ARNSTEIN, M.D., BOY FRAME, M.D., F.A.C.P., HAROLD M. FROST, M.D.Hypocalcemia — An Unusual Metabolic Complication of Breast CancerGluten-Sensitive Enteropathy with Osteomalacia but without Steatorrhea 1 June 1961Volume 54, Issue 6Page: 1280-1289KeywordsAnemiaCalciumExcretionGastrointestinal tractKidneysLower back painStiffnessUrea Issue Published: 1 June 1961 PDF downloadLoading ...