Abstract
A serosurvey conducted in a sample of first quarter pregnant women in France at week 48-49 of 2009 exhibit a seroprevalence level of 10.6%. It has been extrapolated in male and female population living in France mainland, aged 20-39 yr, that 1,712,000, 95%CI (1,112,700 – 2,311,300) people were recently infected by H1N1pdm (recently vaccinated women were excluded from analysis). From week 36 to 46-47 of 2009, 336,288, 95%CI (207,303-421,299) patients visited their general practitioners with clinical influenza in France, mainland. We then extrapolated the proportion of symptomatic H1N1pdm influenza in both males and females aged 20-39 yr who visited their GP to be 19.6%.
Highlights
Based on results of previous tests performed in a sample of the general population and on the follow up of microbiologically documented infections, only dilution above 1/40 were considered to be relevant for detection of recent H1N1pdm infections in this age group
The Sentinelles Network (UMR-S 707, Inserm and University Pierre and Marie Curie) is a network of 1300 volunteer general practitioners, working throughout the metropolitan regions of France (2% of the total general practitioners in these regions). This national electronic system of clinical surveillance permits the real-time surveillance of the incidence of influenza-like illness (ILI) seen in general practice
Using a periodic regression model applied to historical surveillance data, the excess consultations for influenza-like illness is estimated each week
Summary
We have launched a regular seroprevalence survey among a sample of consecutive pregnant women who systematically visit a laboratory from a predefined network of labs for giving their blood for toxoplasmosis serology. Data on age and recent exposure to H1N1pdm vaccination were collected. Blood samples were shipped to Marseilles by express mail, where a standard HI assay using human group O erythrocytes and 4 HI units of non inactivated H1N1pdm virus was performed in a L3 laboratory.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
