Symphic smallpox, a reemerging disease. Mini-review

Abstract

Smallpox is a zoonotic disease spread primarily through direct contact with body fluids and active blistering wounds in the dermis of an infected person. The virus is believed to have been first isolated in 1958, the first case in an infant was reported in 1970, and an outbreak occurred in Central Africa (Democratic Republic of Congo) in May 2022. The pathology gradually worsened and then continued to spread outside the territory. When we talk about a new virus, it is necessary to understand the epidemiological pattern in space, which is different from the surface of the classical epidemic, and to know the available methods of prevention and antiviral treatment that can be considered, to know it is necessary to know the scientific evidence of how the virus appeared in our country. Antiviral drugs have been shown to be effective against the pathology in animal models and are clinically well tolerated. This resurgent pathology forces us to update our knowledge on the behavior, composition, treatment and use of smallpox vaccines, as they have proven to be useful against monkeys, so we need an evidence-based medical research literature to guide us in this matter. adopt new methods of prevention