Abstract
Purpose: To attempt a new treatment for severe long-standing diarrhea and abdominal pain from microscopic colitis. Materials and Methods: Dextroamphetamine sulfate was prescribed to a 42-year-old woman with progressively worsening microscopic colitis. Results: Within one month she showed a 90% improvement. Conclusion: Dextroamphetamine sulfate immediately caused marked improvement in her diarrhea and pain in one month despite 35 years of suffering.
Highlights
In some instances, even when a condition exists that is very likely to be related to the increased cellular permeability, e.g., pelvic pain, it is possible that correcting other problems can achieve a pregnancy without correcting the permeability defect or negate the heightened activity of the cellular immune system by adding more progesterone [5, 9, 10-14]
Since endometriosis has been associated with infertility, and endometriosis has been associated with increased cellular permeability of pelvic tissues, with dramatic relief by treatment with amphetamine, it would seem reasonable to initiate treatment with dextroamphetamine sulfate initially along with other corrective therapy in women presenting with infertility and pelvic pain [15-17]
Sometimes a woman may present with chronic pelvic pain, Mittelschmerz, dysmenorrhea, and inflammatory bowel disease, e.g., Crohn’s disease, with marked improvement of all symptoms following treatment with sympathomimetic amine, especially those containing dextroamphetamine sulfate [18]
Summary
Sympathomimetic amine therapy abrogates severe long-term unexpalined abdominal pain and diarrhea (microscopic colitis) – possible infertility implications.
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