Abstract
1. 1. A comparison is made between the sympatho-adrenal regulation of subcutaneous adipose tissue blood flow in the dog and in man. 2. 2. In the dog neuronally released noradrenaline causes vasoconstriction in subcutaneous adipose tissue by preferential activation of α-adrenoceptors located close to the sympathetic nerve terminals. 3. 3. In man sympathetic reflex activation also causes vasoconstriction in subcutaneous adipose tissue, presumably via activation of α-adrenoceptors. 4. 4. The adipose tissue vascular β-adrenoceptors are of the β 1-subtype in the dog and the β 2-subtype in man. 5. 5. Because of this adrenaline causes vasoconstriction in dog adipose tissue and vasodilation in human adipose tissue.
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