Abstract
Sympathetic nervous system activity in health and disease—advances with microneurographic recordings
Highlights
Sympathetic neural drive is dependent on a range of factors including race, sex, and age
Evidence derived from studies examining muscle (vasoconstrictor) sympathetic nerve activity (MSNA) during phases of the menstrual cycle, pre- and post-menopause or during pregnancy highlights the role of sex hormones in neural control in women
Ichinose and Nishiyasu (2012) used multiunit MSNA to assess the arterial baroreflex (ABR) control under orthostatic stress and proposed that enhancement of the ABR control under orthostatic stress is an excellent defence against orthostatic hypotension and suggest that impairment of ABR control over sympathetic vasomotor activity leads to the severe hypotension associated with orthostatic syncope
Summary
Sympathetic neural drive is dependent on a range of factors including race, sex, and age. This idea is developed further in the review of Fu (2012) who points out that the sex and age-related differences in the prevalence of hypertension and cardiovascular disease in humans may be determined, at least in part, by differences in sympathetic control.
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