Abstract

The endogenous opioid peptides dynorphins and enkephalins may be involved in brain-area specific synaptic adaptations relevant for different stages of an addiction cycle. We compared the levels of prodynorphin ( PDYN ) and proenkephalin ( PENK ) mRNAs (by qRT-PCR), and dynorphins and enkephalins (by radioimmunoassay) in the caudate …

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