Abstract
AbstractThe novel free radical‐based cleavage of the enaminone C=C double bond is realized by using N‐halosuccinimides (NXS) in the presence of benzoyl peroxide (BPO) with mild heating, enabling the tunable synthesis of α,α‐dihalomethyl ketones and α,α,α‐trihalomethyl ketones under different reaction conditions. The formation of these divergent products involving featured C=C double bond cleavage requires no any metal reagent, and represents one more practical example on the synthesis of poly halogenated methyl ketones via the functionalization of carbon−carbon bond.magnified image
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have