Abstract
Obesity is characterized by the excess of body fat and, therefore, may cause musculoskeletal alterations that can negatively influence the tendons. Such overweight-influenced alterations are exercise sensitive though. Morphological and biochemical alterations were reported in the calcaneal tendon of mice submitted to a lipid-rich diets along with practicing exercises, with the following groups: normal diet without exercise (ND), normal diet with exercise (NDex), lipid-rich diet without exercise (LD), lipid-rich diet without exercise (LDex). The calcaneal tendons were removed and subjected to histological and biochemical analysis. Layers of the tissue were stained with Hematoxylin and Eosin, Picrosirius Red and Von Kossa while a protein dosage was conduce by the Bradford method. The morphologicals analysis there was no statistical difference concerning the number of fibroblasts among the groups. Groups submitted to exercises showed higher amount of collagen and non-collagenous protein deposition. The lipid-rich diet without exercse group had a more disorganized collagen matrix with intense basophilia. The same group had areas of calcification confirmed by Von Kossa technique. Practicing physical activity, such as swimming, can improve the changes caused in the calcaneal tendon in mice submitted to a lipid-rich diets, having a better collagen organization and the synthesis.
Highlights
Calcaneal tendon is the largest and the most rigid tendon in the human body and is responsible for fixing soleus and gastrocnemius muscle to the calcaneus bone (Threvendran et al 2013).This fibrous cord has attracted particular attention, for its importance to Sports Medicine (Benjamin et al 2004, Shaw & Benjamin, 2007)
Body weight and adiposity Animals had their weights monitored during the period they were submitted to the swimming exercise
Regarding the measurement of visceral adiposity, only the group that received normal diet and practiced swimming exercise had the values reduced when compared to the other groups (Fig. 3)
Summary
Calcaneal tendon is the largest and the most rigid tendon in the human body and is responsible for fixing soleus and gastrocnemius muscle to the calcaneus bone (Threvendran et al 2013).This fibrous cord has attracted particular attention, for its importance to Sports Medicine (Benjamin et al 2004, Shaw & Benjamin, 2007). Either degeneration of the tendon is definited as tendinopathy this can be caused by obesity and lead various symptoms such as pain, edema, and compromised performance (Gaida et al 2008). The obesity is most often influenced by consumption of high-fat (Feoli et al 2003). Nogueira et al (2017), studying effects of animals submitted to lipid-rich diet within animals, found that the animals having a diet with high amount of lipids present glycemic levels, body weight and visceral adiposity increased (Nogueira et al 2017). There are two general hypotheses about association of obesity and tendinopathy. The obese individual may develop tendon damage due joint and tendon overload or otherwise the
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