Abstract
Purpose To describe the reliability and the limits of bursa premacularis (BPM) evaluation using a swept source optical coherence tomography (SS-OCT) device with enface and 16 mm-high definition (HD) longitudinal scans. Methods 60 eyes of 60 subjects were enrolled and imaged with SS-OCT system (PLEX Elite 9000, Carl Zeiss Meditec Inc., Dublin, CA, USA). BPM area was measured using enface scans imported to ImageJ. HD horizontal and vertical longitudinal scans centered at the fovea were used to detect width (W) and central thickness (CT) of BPM at baseline (T0) and after 30 minutes (T30) performed by two different observers. An enhanced vitreous visualization software provided by the manufacturer of the device was used to highlight vitreous structures. Results BPM was identifiable in 100% of eyes using both horizontal and vertical longitudinal scans. On horizontal scan, BPM was not entirely measurable in 21.7% and in 18.3% of cases at T0 and T30, respectively. On vertical scan, BPM was not entirely measurable in 75.0% and in 81.7% at T0 and T30, respectively. No statistically significant differences were found between the two different time measurements with an intraclass correlation coefficient above 70%. Median BPM area was 26.9 (Q1-Q3: 19.5-40.5) mm2. In en face imaging, the most frequent BPM shape was the boat one. Conclusion SS-OCT is a reliable tool for a detailed quantification and mapping of BPM, and it is able to add useful details about the morphological BPM features in youth population. However, the enhanced visualization of the vitreous structures is still a challenge, also with the most forefront devices.
Highlights
The Bursa Premacularis (BPM) represents a small reservoir of liquid vitreous located anteriorly to the fovea and is present in all eyes in the first decades of life [1,2,3]. Another distinct empty pocket of the posterior vitreous body and located over the optic disc is called the area of Martegiani (AM) [1,2,3]
Time-domain optical coherence tomography (OCT) helped to depict the vitreous cortex when it was detached from the retina; the imaging failed to show the inner structure of the vitreous [6]
BPM was identifiable in 100% of eyes using both horizontal and vertical longitudinal scans
Summary
The Bursa Premacularis (BPM) represents a small reservoir of liquid vitreous located anteriorly to the fovea and is present in all eyes in the first decades of life [1,2,3].Another distinct empty pocket of the posterior vitreous body and located over the optic disc is called the area of Martegiani (AM) [1,2,3].Further observations were obtained in autopsy eyes in which the vitreous gel had been stained with fluorescein [4].Later triamcinolone-assisted vitrectomy allowed intraoperative visualization of the BPM [5]. The Bursa Premacularis (BPM) represents a small reservoir of liquid vitreous located anteriorly to the fovea and is present in all eyes in the first decades of life [1,2,3]. Another distinct empty pocket of the posterior vitreous body and located over the optic disc is called the area of Martegiani (AM) [1,2,3]. Further observations were obtained in autopsy eyes in which the vitreous gel had been stained with fluorescein [4]. Time-domain optical coherence tomography (OCT) helped to depict the vitreous cortex when it was detached from the retina; the imaging failed to show the inner structure of the vitreous [6].
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