Swelling of the salivary glands and sicca symptoms in Kimura's disease, arare rheumatological differential diagnosis with an indicatively high IgE serum level-Acurrent overview after literature search

Abstract

Rheumatic and musculoskeletal diseases (RMD) include various diseases with sometimes rather different symptoms, some of which are locally confined and others show systemic features. Autoimmune phenomena, such as those occurring in Sjögren's syndrome, often cause symptoms such as xerostomia and xerophthalmia in association with inflammation of the salivary glands. The pathogenesis of these diseases is only partly clarified. This is similar to allergic diseases, which are otherwise clearly different with respect to the symptoms and pathomechanisms but swelling of the salivary glands can also rarely occur here. As this is apossible differential diagnosis of Sjögren's syndrome or also IgG4-associated diseases, and such acase was recently described, aliterature search was carried out in PubMed, the results of which are presented here and summarized in this article in abrief overview.