Abstract

PurposeTo estimate Swedish experience-based value sets for EQ-5D health states using general population health survey data.MethodsApproximately 45,000 individuals valued their current health status by means of time trade off (TTO) and visual analogue scale (VAS) methods and answered the EQ-5D questionnaire, making it possible to model the association between the experience-based TTO and VAS values and the EQ-5D dimensions and severity levels. The association between TTO and VAS values and the different severity levels of respondents’ answers on a self-rated health (SRH) question was assessed.ResultsAlmost all dimensions (except usual activity) and severity levels had less impact on TTO valuations compared with the UK study based on hypothetical values. Anxiety/depression had the greatest impact on both TTO and VAS values. TTO and VAS values were consistently related to SRH. The inclusion of age, sex, education and socioeconomic group affected the main effect coefficients and the explanatory power modestly.ConclusionsA value set for EQ-5D health states based on Swedish valuations has been lacking. Several authors have recently advocated the normative standpoint of using experience-based values. Guidelines of economic evaluation for reimbursement decisions in Sweden recommend the use of experience-based values for QALY calculations. Our results that anxiety/depression had the greatest impact on both TTO and VAS values underline the importance of mental health for individuals’ overall HRQoL. Using population surveys is in line with recent thinking on valuing health states and could reduce some of the focusing effects potentially appearing in hypothetical valuation studies. Electronic supplementary materialThe online version of this article (doi:10.1007/s11136-013-0496-4) contains supplementary material, which is available to authorized users.

Highlights

  • EQ-5D is a generic health-related quality of life (HRQoL) instrument from which a single-index value of the respondent’s health status can be derived, based on a health profile consisting of five dimensions with three severity levels [1]

  • Anxiety/depression had the greatest impact on both time trade off (TTO) and visual analogue scale (VAS) values

  • Our results that anxiety/depression had the greatest impact on both TTO and VAS values underline the importance of mental health for individuals’ overall HRQoL

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Summary

Results

Of the 243 possible health states of the EQ-5D descriptive system, 148 health states were reported and valued. A Swedish TTO value set, based on Model 4, for the 243 EQ-5D health states, is presented in Online Resource Table S3. A Swedish VAS value set, based on Model 4, for the 243 health states, is presented in Online Resource Table S3. Comparison of TTO and VAS values for Models 2 and 4 is presented in Online Resource Table S6 (pooled data) and Table S7 (by survey). Corresponding results of the regression analysis on individual TTO and VAS values for SRH levels are presented in Online Resource Table S8. The TTO and VAS values for the different severity levels for SRH are presented in Online Resource Table S9. Comparison of TTO and VAS values for SRH levels is presented in Online Resource Table S10 (pooled data) and Table S11 (by survey)

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