Abstract
A procedure for benzylic Suzuki–Miyaura cross-coupling under microwave conditions has been developed. These conditions allowed for heterocyclic compounds to be coupled. Optimum conditions found were Pd(OAc) 2, JohnPhos as the catalyst and ligand, potassium carbonate as the base, and DMF as the solvent. Using these conditions, a library of structurally diverse compounds was synthesized.
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