Sutures

Abstract

Abstract Surgical sutures are sterile, flexible strands used to close wounds or to tie off tubular structures such as blood vessels. They may be made from natural or synthetic fibers and are usually attached to a needle. The generic and proprietary names of the natural and synthetic polymeric fibers used in the manufacture of surgical sutures distributed commercially in the United States are given, along with the claims for retention of strength at various intervals and the time required for absorption. The various structures of sutures are discussed in terms of biological compatibility, diameter and strength standards, and methods of sterilization. Color additives and coatings for each type of suture are described, as are the accompanying needles. Regulatory requirements are discussed, and tables of United States Pharmacopeia specifications are given.