Abstract
The C 18 unsaturated dendritic amphiphiles of different generations were examined as an encapsulating agent for hydrophobes. The DLS studies demonstrated the nano-aggregation and encapsulation of pyrene within the hydrophobic cores & pyrene excimer formation, and its sustained pH-dependent release was observed by UV–Vis spectroscopy. The sustained release of pyrene from the core of micelles was studied to estimate the temperature and pH susceptibility of the ester linker. The non-ionic ester-linked amphiphiles of all three generations showed a significant encapsulation of dye at pH 7.0. The results of sustained release of hydrophobic dye at 37 ○ C in 24 h to 48 h of treatment with a solution of pH 6.2, 7.4 and 8.2 are remarkable.
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