Abstract
Acute Disseminated Encephalomyelitis (ADEM) is an immune-mediated demyelinating disease of the Central Nervous System clinically defined by acute polyfocal neurological syndrome usually following a monophasic course. ADEM often occurs after infections, but 5-10% of cases are preceded by vaccinations. Several cases of ADEM after SARS-CoV-2 infection have been described, whereas no cases have been reported after administration of mRNA/adenovirus COVID-19 vaccines. Here, we describe a suspected case of ADEM presenting two weeks after receiving the first dose of ChAdOx1 nCoV-19 vaccine.
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