Abstract
This study investigated the antibiogram profile of <em>Serratia marcescens</em> among hospitalized individuals, hospital environments and halls of residence of Obafemi Awolowo University in Ile Ife, Osun state with a view to provide key information on resistance factors that are of therapeutic importance among the understudied pathogen.
Highlights
The frequency of infections and outbreaks due to S. marcescens has steadily increased for 4 decades, especially among infants, the hospitalized and individuals with suboptimal immunity [1]
Antibiotic resistance among Gram negative bacteria is a public health problem of global relevance; resistance among Serratia sp. are more worrisome due to their enormous virulence factors, ability to exist in biofilm resulting in polymicrobial infections, chromosomal resistance factors e.g. enzymes and genes as well as those that could be acquired as plasmids [2]
All samples were transferred to the laboratory for immediate cultures on freshly prepared sorbitol MacConkey agar infused with 200 U/ml of colistin
Summary
The frequency of infections and outbreaks due to S. marcescens has steadily increased for 4 decades, especially among infants, the hospitalized and individuals with suboptimal immunity [1]. Amidst such individuals, unsuccessful antibiotic therapy due to resistance results sometimes to death, permanent organ damage and more often; longer course of infections. Serratia marcescens has been regarded as a pathogen in every conceivable kind of infections [5] ; the presence of underlying immunosuppressive or debilitating conditions is critical to establishment of infection among the hosts [6] These conditions may include heroin addiction [5], ageing [7] prolonged
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