Abstract
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Highlights
Young laboratory Wistar rats and guinea-pigs were infected intraocularly and orally with infectious bursal disease virus (IBDV) suspension which had bursal lesionsO 104 8 per 0.5 mI
agar gel diffusion precipitation test (AGDT) has been found to be less sensitive than virus isolation and immuno-fluoroscopy methods in the diagnosis of IBDV infection (I d e 1975)
0 k 0 y e and U c h e (1986) detected IBDV precipitins in wild rat tissues using AGDT
Summary
Young laboratory Wistar rats and guinea-pigs were infected intraocularly and orally with infectious bursal disease virus (IBDV) suspension which had bursal lesionsO 104 8 per 0.5 mI. 2 out of 3 guinea-pig sera collected 14 days PI were positive for IBDV precipitins while rat sera were negative. These observations show that IBDV infection in guinea-pigs could be subclinical. O k 0 y e and U c h e (1986) detected IBD precipitins in the tissues of wild rats killed with traps set in poultry farms with history of previous IBD outbreaks and suggested that the rats could be involved in the spread of IBD among poultry farms This observation is further investigated in this project in which the response of laboratory rats and guinea-pigs to IBDV infections are studied
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