Abstract
One day in the early 1990s, when Susan Sawyer was training as a paediatrician at the Royal Children's Hospital, Melbourne, Australia, three or four teenage patients with cystic fibrosis came to her with some awkward questions about sex. They were all girls, aged 15–16 years, and “had obviously sat around and asked themselves these questions”, Sawyer recalls. Knowing that most men with the disease are infertile, they wanted to find out about their own fertility and what that meant in terms of contraception.
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