Abstract
The overall survival-time response of the Mongolian gerbil (Meriones unguiculatus) to lethal and supralethal doses of x-radiation has been determined and found to be similar to that of other members of the family Cricetidae and somewhat different from that of other rodents. The central nervous system (CNS) syndrome is similar since the survival time falls from over 100 hours at 15,000 or 20,000 rads to less than 4 hours at 80,000 rads. Similarly, the bone marrow deaths occur within 2 weeks following doses between 840 and 1200 rads. This high minimum lethal value is a characteristic common to certain members of the family Cricetidae, and is exceptional and unique among these radioresistant species. On the other hand, certain inconsistancies were also noted. Animals dying from about 1200 rads to 15,000 or 20,000 rads live for 7 to 10 days after irradiation. This is approximately twice the normal range and it is suggested that it reflects the rate of development of the gastrointestinal (GI) lesion. In additi...
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