Survival Patterns of Hormone Refractory Prostate Cancer in Sulaymaniyah, Iraqi Kurdistan

Abstract

As the most common solid tumor diagnosed among men, prostate cancer is responsible for the death of aremarkable number of men worldwide every year. The present study was carried out in order to figure outthe survival patterns and the effective variables in patients with hormone refractory prostate cancer. Usinga retrospective cohort design with a nested case-control study approach, the present study was carried outon 150 patients with prostate cancer at Hiwa Cancer Hospital located in Sulaimania, the Iraqi Kurdistanin 2014. The patients were assigned into a case group (who developed resistance to androgen deprivationtherapy) and a control group (who did not develop resistance to androgen deprivation therapy within the firstthree years of prostate cancer treatment). The required data were collected through a researcher-designedquestionnaire and using the patients’ hospital records. Most of the patients aged between 65 to 80 years.According to the results, the highest survival probability belonged to the age group 60-80, while the lowestwas related to those aged less than 60 years, and there was no significant relationship between age groupsand overall survival (p>0.05). Prostate cancer is more likely to develop in males aged 65 to 80 year. Theypatients’ overall survival is not correlated with their age, while there is a correlation between the stageof their tumors and their overall survival. The patients’ their progression-free survival was found to besignificantly affected by their age and histopathology, while the stage of their tumors was not in a significantcorrelation with their progression-free survival.