Abstract

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide, with a 5-year survival rate of 15%. Polysomy is commonly seen in a wide variety of cancers and plays an oncogenic role. A fusion oncogene consisting of an inversion in chromosome 2, anaplastic lymphoma kinase (ALK)-echinoderm microtubule-associated protein-like 4 (EML4), is …

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