Abstract
IntroductionThe survival of HIV/AIDS patients on antiretroviral therapy (ART) is determined by a number of factors, including economic, demographic, behavioral, and institutional factors. Understanding the survival time and its trend is crucial to developing policies that will result in changes. The aim of this study was to compare the survival estimates of different subgroups and look into the predictors of HIV/AIDS patient survival.MethodsA retrospective cohort study of HIV/AIDS patients receiving ART at the University of Gondar teaching hospital was carried out. To compare the survival of various groups, a Kaplan-Meier survival analysis was performed. The Cox proportional hazards model was used to identify factors influencing HIV/AIDS patient survival rates.ResultsIn the current study, 5.91% of the 354 HIV/AIDS patients under ART follow-up were uncensored or died. Age (HR = 1.051) and lack of formal education (HR = 5.032) were associated with lower survival rate, whereas family size of one to two (HR = 0.167), three to four (HR = 0.120), no alcoholic consumption (HR = 0.294), no smoking and chat use (HR = 0.101), baseline weight (HR = 0.920), current weight (HR = 0.928), baseline CD4 cell count (HR = 0.990), baseline hemoglobin (HR = 0.800), and no TB diseases were associated with longer survival rate.ConclusionsFewer deaths were reported in a study area due to high patient adherence, compared to previous similar studies. Age, educational status, family size, alcohol consumption, tobacco and chat usage, baseline and current weight, baseline CD4 cell count, baseline hemoglobin, and tuberculosis (TB) diseases were all significant predictors of survival of HIV/AIDS patients.
Highlights
The survival of Human immunodeficiency virus (HIV)/Acquired immune deficiency syndrome (AIDS) patients on antiretroviral therapy (ART) is determined by a number of factors, including economic, demographic, behavioral, and institutional factors
Study design A retrospective study design was used on people living with AIDS who were being treated with ART at the University of Gondar teaching hospital in Gondar, Ethiopia
The risk of death for illiterate HIV/AIDS patients on ART follow-up was 5.032 times higher than for patients with a secondary or higher educational status (HR = 5.032, 95% Confidence interval (CI) 1.129, 22.423)
Summary
The survival of HIV/AIDS patients on antiretroviral therapy (ART) is determined by a number of factors, including economic, demographic, behavioral, and institutional factors. Acquired immune deficiency syndrome (AIDS) is the world’s most serious public health problem. It affects over 35 million people worldwide [1]. Understanding the survival experience of AIDS patients, as well as the factors that influence survival, is critical for According to previous research, approximately one million people in Ethiopia were infected with HIV in 2008 [4]. Survival trends following HIV infection in African populations prior to the introduction of ART were used as a baseline for assessing future success of intervention programs [5]. Despite the availability of a large body of research that confirms the facts about
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