Abstract
e17527 Background: Cervical cancer (CC), being a high-incidence pathology in Ecuador, requires a priority multidisciplinary therapeutic approach to obtain an optimal benefit in overall survival. The objective of the present study is to describe overall survival (OS) in patients with locally advanced CC treated with chemoradiation according to histological type and clinical stage. Methods: It is an observational, analytical, retrospective, longitudinal study of patients with stage IIB-IVA CHD who received treatment with chemoradiation from January 2010 to December 2014 with a 10-year follow-up. The SPSSv29 statistical system was used. Survival analysis was performed using the Kaplan-Meier method and the Log-Rank test. Results: Of 1909 patients, 1581 were excluded because they did not meet eligibility criteria. 328 received chemoradiation. The overall survival result was 43%. According to histological type, 276 patients presented squamous cell carcinoma (SCC) and 52 adenocarcinoma (AC), presenting a survival of 44% for SCC and 35% for AC. The calculation by clinical stage, II-B shows a survival of 46%. For stage IV-A 20% up to 46 months. The Log-Rank test (p=0.04) shows a significant statistical value. Conclusions: The 10-year overall survival was 43%, showing an essential difference for the histological type, being higher for squamous cell carcinoma, and also showing a significant difference between the stages. [Table: see text]
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