Survival in Hodgkin disease. A study of patients with at least ten-year survival.

Abstract

A retrospective study of 250 patients with Hodgkin disease was done to compare 39 survivors of 10 years to 26 survivors of less than 3 years from time of diagnosis. Factors of significance between survivors of Hodgkin disease of less than three years and those of more than ten years are fever, weakness, cough, dyspnea, anorexia, extensive axillary or inguinal nodes, mediastinal involvement, performance status less than 90%, stage of disease at diagnosis (stage I or II), and favorable histologic findings (lymphocyte predominance or nodular sclerosing). Other factors are of less or little significance. The predominance of long-term survivors whose disease was diagnosed up to 1961 were in stage I or II by retrospective analysis. Long periods of remission between treatments correlated with long survival.