Abstract

Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis, and mainly transmitted via faecal-oral contamination or consumption of contaminated food products. However, limited data on the surface stability and HEV sensitivity to chemical disinfectants are available. To establish an HEV-based carrier assay to evaluate its surface stability and the virucidal activity of nine surface disinfectants. A recently developed robust HEV-3cell culture system for an HEV-based carrier assay. Alcohol-based disinfectants were insufficient to eliminate HEV infectivity, whereas disinfectants based on aldehyde, peracetic acid, oxygen, and/or quaternary ammonium inactivated HEV. These findings have strong implications for the recommendation of evidence-based hygiene guidelines to reduce HEV transmission.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call