Abstract
This article aims to estimate the specific survival of patients with penile cancer treated at a state tertiary oncology hospital. The study included 100 cases incidents patients with penile cancer treated at a cancer center, from 2000 to 2011, follow-up to December 31, 2012. The hospital-based cancer registry and medical records were used as data sources. We used the Kaplan-Meier method to estimate survival and the Cox model was used to assess prognostic factors. All had histology for penile cancer as a basis for diagnosis. For location of the 75% tumor were not specified, followed by 18% located in the glans, 04% in the foreskin. The median survival time was 49 months, 89% presented themselves between stages I and II. Patients with rural occupations had a mean survival time of 75.02 months, patients with non-rural occupations 42.14 months; Patients residing in metropolitan area - Espírito Santo had a mean survival time of 26.03 months, other patients 71.42 months; In patients with compromised lymph nodes, the mean survival time was 30.59 months, and in patients with no compromised lymph nodes, the mean survival time was 75.83 months. This study demonstrates reduced survival in non-rural workers who reside in metropolitan area and who present with compromised lymph nodes and metastasis.
Highlights
The incidence of penile cancer varies around the world, and penile cancer is generally considered a rare cancer[1] with an incidence of 0.6 per 1,000,000/year[2]
This article aims to estimate the specific survival of patients with penile cancer treated at a state tertiary oncology hospital
This study demonstrates reduced survival in non-rural workers who reside in metropolitan area and who present with compromised lymph nodes and metastasis
Summary
The incidence of penile cancer varies around the world, and penile cancer is generally considered a rare cancer[1] with an incidence of 0.6 per 1,000,000/year[2]. In developing countries, penile cancer is observed more frequently[3], in Africa and South America, and the environmental factors, chronic papillomavirus infections and poor hygienic conditions play an important role in occurrence of penile cancer.[1]. Penile cancer has a high mortality rate[4], ranging from 26.7 to 41%5. The incidence rates vary among different populations, with the highest cumulative rates seen in parts of Uganda and 300-fold less, found among Israeli Jews[1]. In Brazil represents 2% of male cancers in 2013 was responsible for the deaths of 396 men[6]. Complications deriving from tumour growth in areas of lymphatic spread, such as necrosis, sepsis, cachexia, and bleeding resulting from the erosion of the femoral vessels[9]
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