Abstract

Objective To compare the survival conditions of patients with insulinoma after enucleation of insulinoma or partial resection of pancreas. Methods The clinical data of 99 patients with insulinoma, treated with surgery from May. 2003 to Aug. 2015 were retrospectively analyzed. Of the 99 patients, 38 received enucleation of insulinoma alone and 61 received partial resection of pancreas. The overall data were analyzed by SPSS 21.0 software. Results Average survival of patients after enucleation of insulinoma (103.3 months) was longer than that of patients after partial resection of pancreas (77.5 months) , and the difference had statistical significance (P=0.006) . The difference of the incidence of most chronic or temporary complications had no statistical significance between the two groups (P>0.05) , except for new-onset diabetes (P=0.004) . Conclusion Enucleation of insulinoma should be firstly recommended for patients with insulinoma in suitable size, which can provide patients with better survival condition. Key words: Insulinoma; Surgical procedures; Survival analysis

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