Abstract

Rationale: The increase of resting energy expenditure (REE) variation in ALS is a prognostic factor for the survival mainly in patients with a REE variation over +20%. Measurement of REE by indirect calorimetry (IC) compared to REE predicted with formula (Harris and Benedict [HB] 1919, HB 1984 or Mifflin) is necessary to obtain the REE variation. However, IC is not available in many centres. Jésus et al. formula is a validate formula to predict REE in ALS and can be used in the absence of an IC. The aim of this work was to study the survival of ALS patients according to REE variation with IC or Jésus formula.

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