Abstract

BackgroundA wide variety of ontologies relevant to the biological and medical domains are available through the OBO Foundry portal, and their number is growing rapidly. Integration of these ontologies, while requiring considerable effort, is extremely desirable. However, heterogeneities in format and style pose serious obstacles to such integration. In particular, inconsistencies in naming conventions can impair the readability and navigability of ontology class hierarchies, and hinder their alignment and integration. While other sources of diversity are tremendously complex and challenging, agreeing a set of common naming conventions is an achievable goal, particularly if those conventions are based on lessons drawn from pooled practical experience and surveys of community opinion.ResultsWe summarize a review of existing naming conventions and highlight certain disadvantages with respect to general applicability in the biological domain. We also present the results of a survey carried out to establish which naming conventions are currently employed by OBO Foundry ontologies and to determine what their special requirements regarding the naming of entities might be. Lastly, we propose an initial set of typographic, syntactic and semantic conventions for labelling classes in OBO Foundry ontologies.ConclusionAdherence to common naming conventions is more than just a matter of aesthetics. Such conventions provide guidance to ontology creators, help developers avoid flaws and inaccuracies when editing, and especially when interlinking, ontologies. Common naming conventions will also assist consumers of ontologies to more readily understand what meanings were intended by the authors of ontologies used in annotating bodies of data.

Highlights

  • A wide variety of ontologies relevant to the biological and medical domains are available through the Open Biomedical Ontologies (OBO) Foundry portal, and their number is growing rapidly

  • Survey To determine the sources of heterogeneity in naming and to initiate a discussion among the ontology groups associated with the OBO Foundry, we carried out a survey

  • Consensus-based conventions to guide ontology development are a crucial requisite for the achievement of this goal

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Summary

Introduction

A wide variety of ontologies relevant to the biological and medical domains are available through the OBO Foundry portal, and their number is growing rapidly Integration of these ontologies, while requiring considerable effort, is extremely desirable. One of the goals of the Open Biomedical Ontologies (OBO) Foundry initiative [2] is to facilitate integration among these diverse ontologies Such integration demands considerable effort and differences in format and style can only add obstacles to the execution of this task [3]. We focus on issues of nomenclature [4], and on the naming conventions used for labeling classes in ontologies, which are an additional contributing factor to the problem of heterogeneity Even in this relatively straightforward area, no conventions have achieved broad acceptance (see survey section below)

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