Abstract

Age-related Macular Degeneration (AMD) is the most common eye disease that causes visual impairment in elder people. Prevalently, AMD is detected by Spectral Domain Optical Coherence Tomography (SD-OCT) for diagnosis and monitoring purposes. In this work, 50 papers are reviewed to examine various approaches and their performance metrics. This paper reviewed various existing works related to AMD detection using different imaging modalities for quality images with high resolution. The investigation of case studies is analyzed on the basis of data collected from various patients undergoing several treatments and scans obtained from various imaging modalities. Furthermore, the analysis extends to the works that used different AI techniques, such as Deep Learning (DL), Machine Learning (ML), and Unsupervised Framework, for the detection of AMD-related diseases. Also, the analysis of different performance measures is done that shows the variations in terms of performance metrics such as accuracy, sensitivity, specificity, and so on. The outcome of this deep analysis shows that the system with the DL model reaches its utmost performance in AMD detection. Finally, gaps and challenges that are still lagging with this research area are summarized, which motivates the researchers to take away the work in an effective way.

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