Abstract
Tissue samples were collected to survey tetracycline antibiotics (TCs) residues in slaughtered animals that did not pass inspection, because of the presence of disease symptoms, at slaughterhouses in Aichi Prefecture, Japan, from January, 1992 to December, 1994. The tissues were analyzed by HPLC. Among 39 animals (cattle: 9, hog: 30) in total, 11 (28.5%) were positive for oxytetracycline and 7 (17.9%) for chlortetracycline.However, tetracycline and doxycycline were not detected in any sample. Percentage frequencies of TCs residues were 22.2% (2/9) and 30.0% (9/30) for cattle and hogs, respectively. Kidney samples showed higher incidence of TCs residues and 1.6-6.9 times higher residual concentrations than liver and miscellaneous samples, indicating that inspection of slaughtered animal's kidneys for residual TCs is the most effective means of monitoring the safety of foods.
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