Abstract
Keratoconjunctivitis sicca (KCS, dry eye) is a common cause of ocular morbidity and blindness in dogs. Typical clinical signs are mucoid to mucopurulent discharge, rubbing and pawing eyes, and progressive corneal scarring. Canine KCS can result from a number of causes including trauma, canine distemper virus, and sulfonamide toxicity, but most cases are thought to have an autoimmune pathogenesis.1–4 Like human dry eye, canine dry eye may occur as an isolated disorder or in association with a number of autoimmune diseases, such as atopy, hyperadrenocorticism, diabetes mellitus, and hypothyroidism.4,5
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