Abstract
Background: It is not clear if more intense surveillance isassociated with improved survival after curative resectionfor gastric cancer. Patients and Methods: A prospectivelymaintained gastric cancer database was used toidentify 402 patients who underwent curative gastrectomy.Multivariate analysis was performed to identify theclinicopathological characteristics associated with longpost-recurrence survival. Results: Of 402 patients, 62 patientsshowed documented recurrence. As shown bymultivariate analysis, patients with lymph node metastasesoriginating from primary cancer, symptomatic recurrence,peritoneal dissemination, multiple recurrencesand supportive therapy showed a significantly shorterpost-recurrence survival. Patients who suffered hematogenousmetastases, locoregional recurrence, or recurrencein the remnant stomach had a significantly longersurvival time when treated actively compared with thosegiven supportive care. Conclusion: Active treatment is effectivein patients with hematogenous metastases, locoregionalrecurrence, or recurrence in the remnantstomach. Intense surveillance is thus recommended forearly identification of such patients.
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