Abstract
What is already known about this topic? Vaccinations are the most effective way to prevent influenza virus infections and severe outcomes. Influenza vaccine effectiveness can vary by seasons. What is added by this report? This report monitors the antibody level among the population over time after administration of the quadrivalent or trivalent split influenza vaccine. What are the implications for public health practice? Real-time monitoring of serum antibody changes after vaccination provides important data for the development of reasonable and effective strategies for influenza prevention and control.
Highlights
The World Health Organization (WHO) estimates that 5%–10% of the world population each year becomes infected with the seasonal influenza virus, mainly influenza A and B viruses, resulting in approximately one billion influenza cases [1], 3–5 million cases of severe illness, and 290,000–650,000 fatal cases [2]
There have been four influenza pandemics in history caused by the influenza A virus including the 1918 Spanish flu [A(H1N1)], the 1957 Asian flu [A(H2N2)], the 1968 Hong Kong flu [A(H3N2)], and the 2009 swine-origin flu [A(H1N1) pdm09] [3]
There was no statistical difference in the seroconversion rates against H1N1 and H3N2 between the IIV4s and IIV3s vaccine groups
Summary
The age distribution of the IIV4s and IIV3s vaccination groups in different gender was balanced (Supplementary Table S2, available in http://weekly.chinacdc.cn/). The seroconversion rates against H1N1, H3N2, B/Victoria, and B/Yamagata in the IIV4s-vaccinated subjects were 69.4% (50/72), 59.7% (43/72), 54.2% (39/72), and 51.4% (37/72), respectively. The seroconversion rates against H1N1, H3N2, and B/Victoria in the IIV3s vaccine recipients were 79.7% (59/74), 70.3% (52/74), and 36.5% (27/74), respectively.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
