Abstract
The present work describes the occurrence of two conidiobolomycosis outbreaks in Santa Ines breedsheep, in the state of Bahia. The first outbreak (FO) occurred in a property located in Santo Estevao city,involving three animals, and the second outbreak (SO) occurred in a property in Entre Rios city, affecting one sheep. In both outbreaks, the clinical findings were characterized by progressive weight loss, dyspnea, andbloody serous nasal discharge. In the FO was also observed unilateral craniofacial asymmetry, associatedwith exophthalmia and epiphora of the right eye. Autopsies performed on the three FO sheep showeda large mass predominantly yellowish-white with red-black areas of the uneven surface, finely granular,moist and crumbly located in the ethmoidal region, invading the nasopharyngeal, choana, sinuses, retrobulbar region, who infiltrated the cribriform plate and reached the meninges. In two sheep of the FO, themass reached the front portion of the brain. In SO sheep it was found, on the mucous membrane of thenasal vestibule, small red-black multifocal to coalescing nodules, with eroded surface and hyperemiaof the nasal turbinates with hemorrhagic catarrhal secretion, and in the most rostral portion of nasalcavity, the mucosa had a irregular, wet, bleeding and red-black surface, with blackish gray and brownishareas, displaying partial focal destruction of nasal turbinates. Microscopic examination of granulomatouslesions revealed multiple areas of coagulation necrosis containing intense reaction of Splendore-Hoeppliassociated with negative images of fungal hyphae and granulomatous inflammation. In all cases, theGMS and PAS staining showed numerous wide hyphae, with bulbous distension at one end. By PCRtechnique it was characterized Conidiobolus lamprauges by analysis of serum samples of two sheep andparaffin block lesions of one sheep. Immunohistochemical analyzes were positive for C. lamprauges inall animals. It can be proved, for the first time, the occurrence of nasopharyngeal / rhinocerebral andrhinofacial conidiobolomycosis infection by C. lamprauges in the state of Bahia.
Highlights
Tiago da Cunha Peixoto1, Eliene Barbosa de Lima2, Soraya Santos de Farias3, Margareth Moura Ferreira4, Alan Greison Costa Macêdo2, Luciano Nakazato5, Caroline Argenta Pescador6, Mariana Sequeira d’Avila7, Vivian de Assunção Nogueira Carvalho8 & Karina Medici Madureira1*
The present work describes the occurrence of two conidiobolomycosis outbreaks in Santa Ines breed sheep, in the state of Bahia
The first outbreak (FO) occurred in a property located in Santo Estevao city, involving three animals, and the second outbreak (SO) occurred in a property in Entre Rios city, affecting one
Summary
Tiago da Cunha Peixoto1, Eliene Barbosa de Lima2, Soraya Santos de Farias3, Margareth Moura Ferreira4, Alan Greison Costa Macêdo2, Luciano Nakazato5, Caroline Argenta Pescador6, Mariana Sequeira d’Avila7, Vivian de Assunção Nogueira Carvalho8 & Karina Medici Madureira1*. Três ovinos adultos foram acometidos, sendo duas fêmeas (1PS e 2PS) e um macho (3PS), os quais foram encaminhados ao Centro do Desenvolvimento da Pecuária (CDP), da Universidade Federal da Bahia (UFBA), com histórico de epistaxe por 10 dias, emagrecimento progressivo e aumento de volume do globo ocular, com diagnóstico presuntivo de tumor etmoidal enzoótico.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
