Abstract

BackgroundScreening for gestational diabetes mellitus (GDM) is routine during pregnancy in many countries in the world. The screening programs are either based on general screening offered to all pregnant women or risk factor based screening stipulated in local clinical guidelines. The aims of this study were to investigate: 1) the compliance with local guidelines of screening for GDM and 2) the outcomes of pregnancy and birth in relation to risk factors of GDM and whether or not exposed to oral glucose tolerance test (OGTT).MethodsThis study design was a population-based retrospective cross-sectional study of 822 women. A combination of questionnaire data and data collected from medical records was applied. Compliance to the local guidelines of risk factor based screening for GDM was examined and a comparison of outcomes of pregnancy and delivery in relation to risk factor groups for GDM was performed.ResultsOf the 822 participants, 257 (31.3%) women fulfilled at least one criterion for being exposed to screening for GDM according to the local clinical guidelines. However, only 79 (30.7%) of these women were actually exposed to OGTT and of those correctly exposed for screening, seven women were diagnosed with GDM. Women developing risk factors for GDM during pregnancy had a substantially increased risk of giving birth to an infant with macrosomia.ConclusionSurprisingly low compliance with the local clinical guidelines for screening for GDM during pregnancy was found. Furthermore, the prevalence of the risk factors of GDM in our study was almost doubled compared to previous Swedish studies. Pregnant women developing risk factors of GDM during pregnancy were found to be at substantially increased risk of giving birth to an infant with macrosomia. There is a need of actions improving compliance to the local guidelines.

Highlights

  • Screening for gestational diabetes mellitus (GDM) is routine during pregnancy in many countries in the world

  • There were no significant differences in prevalence of risk factors in medical history between the two catchment areas

  • As presented in Additional file 1, women with risk factors in their medical history reported more problems related to life style and had lower educational level

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Summary

Introduction

Screening for gestational diabetes mellitus (GDM) is routine during pregnancy in many countries in the world. The screening programs are either based on general screening offered to all pregnant women or risk factor based screening stipulated in local clinical guidelines. The aims of this study were to investigate: 1) the compliance with local guidelines of screening for GDM and 2) the outcomes of pregnancy and birth in relation to risk factors of GDM and whether or not exposed to oral glucose tolerance test (OGTT). Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance that is initiated or detected during pregnancy [1]. In Sweden, the prevalence of GDM is reported in 1.2 - 2.3% of the pregnant women [3,4,5,6]. Risk factors for GDM may be categorized in maternal or pregnancy-related factors. Elevated levels of fasting plasma glucose [9], repeated glucosuria and elevated levels of random plasma glucose during pregnancy are pregnancy-related risk factors for GDM [10] as well as accelerated foetal growth and polyhydramniosis [11]

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