Abstract
Stage Ⅳ gastric cancer is defined as gastric cancer with non-curative factors, and the long-term survival rate of patients with stage Ⅳ gastric cancer is around 10%. Chemotherapy has been used for the main therapy of the patients with unresectable stage Ⅳ gastric cancer. Palliative resection of the primary tumor has been recommended only for presence of obstruction, bleeding and other surgical emergency. Debulking operation was irrelevant to the outcome that has been considered by research results. However, the patients with stage Ⅳ gastric cancer of only one non-curative factors (No.16a2, b1 lymph node enlargement; degree of peritoneal metastasis as P0 and positive peritoneal cytology; a small number of liver metastases) have good long-term survival when these patients have achieved R0 or R1 resection. In this regard, comprehensive treatment including surgical resection is the main treatment policy for the patients with stage Ⅳ gastric cancer. In recent years, some clini-cal studies on improvement of prognosis through surgical resection after conversion therapy have received extensive attention. Key words: Gastric neoplasms, stage Ⅳ; Surgical procedures, operative; Chemotherapy; Conversion therapy
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