Abstract
PurposePersistent fetal vasculature (PFV), or persistent hyperplastic primary vitreous (PHPV), is a congenital ocular disorder caused by incomplete regression of the embryonic hyaloid vasculature (associated with cataract and glaucoma). Our aim is to overview primary surgical approaches in treatment of PFV with anterior disease based on literature review and two consecutive cases.MethodsReview of published cohort studies and case reports was performed with PubMed Search engine (keywords: PFV, PHPV, lensectomy, vitrectomy, anterior disease). Two consecutive cases of unilateral PFV with anterior disease treated with lensectomy and vitrectomy were analyzed regarding surgery timing and surgical steps.ResultsLiterature review showed limited follow‐up (mean 22–76 months) in cohort studies, as well as variation of timing, surgical approaches, and correction of aphakia. During surgery protection of corneal endothelium, removal of capsular remnants and endodiathermy of the hyaloid artery are critical.ConclusionsTiming of primary surgery in PFV and proper surgical intervention are crucial for the best visual outcome possible. Postoperative period has to include thorough monitoring of intraocular pressure and amblyopia treatment.
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