Abstract

The Japanese Gastric Cancer Treatment Guidelines (the Guidelines), as a guiding and programmatic document in the treatment for gastric cancer, has drawn high attention worldwide. The treatment selection and determination is mainly based on the T staging. Endoscopic therapy, laparoscopic surgery and minimal extent surgery have consisted of the main clinical practice for T1 cancer. D2 dissection is a standard procedure for advanced cancer(T2-T4). Extensive resection or neoadjuvant preoperative chemotherapy is recommended for highly advanced cancer. Progress in gastric cancer treatment has been acquired recently due to high-level clinical trials, new anti-cancer drugs application, and efficiency of chemotherapy. Therefore, traditional extensive resection has been abandoned gradually. Comprehensive treatment based on chemotherapy could improve survival for patients with unresectable and recurrent gastric cancer.

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