Abstract
SESSION TITLE: Cardiothoracic Surgery SESSION TYPE: Original Investigation Slide PRESENTED ON: Sunday, October 29, 2017 at 01:30 PM - 03:00 PM PURPOSE: Evaluate the characteristics of patients with thymic epithelial neoplasms and the effect of different therapeutic modalities available in a tertiary care hospital in Mexico. METHODS: Retrospective, observational study of patients diagnosed with thymic epithelial neoplasms who underwent surgical resection, chemotherapy and/or radiation therapy in a medical referral center. Demographic characteristics as well as information about the treatment received, potential complications and adverse effects were obtained and recorded through review and analysis of clinical records. A survival analysis was conducted taking into account the different treatment arms and clinical stages. RESULTS: In the period from January 1987 to May 2015, a total of 68 patients diagnosed with thymoma were identified in the hospital records. 41 (60%) patients were male and 27 (40%) women with and average age of 49.8 years (19-81). The main comorbidity was myasthenia gravis (66%). All underwent surgery and 23 (34%) received treatment plus chemotherapy and/or radiation. Most adverse effects were presented with surgery (68%). The average follow-up was 5 years. Survival at 5 and 10 years was 84% and 72% respectively. Free period of recurrence at 5 years was 87%. Significant higher 10-year survival prognostic factors were age, stage and type of resection. CONCLUSIONS: The study has a a representative sample of the features described in thymic epithelial neoplasms worldwide, plus several patients have had more than 10 years of monitoring. Survival obtained is similar to that reported in the literature. Surgery is the treatment of choice. The stage of the tumor, complete resection and advanced age are significant factors for overall survival, while the sex of the patient, the presence of myasthenia gravis and histological grade showed not be relevant. The role of radio and chemotherapy should be reevaluated. CLINICAL IMPLICATIONS: Our study is the first of its kind to be performed in our country and its results may be relevant when considering a certain type of treatment and performing the prognosis of each of the patients with thymoma in our institution and others centers of reference in spite of their relative infrequency, since their management represents a medical challenge. DISCLOSURE: The following authors have nothing to disclose: Rocio Carrera-Ceron, Julio Herrera-Zamora, Francina Bolaños Morales, Patricio Santillan-Doherty No Product/Research Disclosure Information
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
