Abstract
Surgical site infections (SSIs) following caesarean surgeries are common. The present study aimed to evaluate the frequency of SSIs following caesareans at Jordan University Hospital during the 30 postoperative days and to identify factors associated with increased SSIs risk. Data regarding the occurrence of SSIs were collected both prospectively via follow-up phone calls and retrospectively via reviewing wound culture results and clinical notes. SSI cases were subsequently determined utilizing predefined criteria. Data relating to possible risk factors of SSIs were collected from patient interviews and hospital records. Risk factors for SSIs were identified via logistic regression. A high rate of SSIs (14.4%) was detected; implicated factors included body mass index ≥36 kg/m2 prior to pregnancy odds ratio (OR) 3.8, 95% confidence interval (95% CI) 1.6–9.4, hospital stay longer than 3.5 days OR 2.3, 95% CI 1.4-3.6, having the operation at a gestational age greater than 40 weeks OR 2.2, 95% CI 1.3-3.9. Receiving a higher weight-adjusted dose of the prophylactic antibiotic cefazolin was associated with lower SSIs risk OR 0.967, 95% CI 0.94-0.99.In conclusion, a high rate of SSIs following caesareans was detected, and modifiable risk factors of SSIs should be incorporated into targeted policies aiming to reduce the rate of SSIs.
Highlights
Based on world health organization (WHO) data, one in three patients receiving a surgical procedure in low-income/middle-income countries is predisposed to be affected by surgical site infections (SSIs)[1]
We examined the impact of non-compliance with two components of the American Society of Health-System Pharmacists (ASHP) guidelines, which are the dose of cefazolin (ASHP recommended 2-g dose vs. 1-g dose) and the duration of antibiotic administration in relation with SSIs
The patient-specific, procedure-specific and practice-specific variables investigated in the present study for their association with SSIs in both the included and the excluded women are shown in Supplementary Table S3
Summary
Based on world health organization (WHO) data, one in three patients receiving a surgical procedure in low-income/middle-income countries is predisposed to be affected by surgical site infections (SSIs)[1]. Of the different types of surgical wound infections, caesarean wound infections are of particular interest, as they are of the main infectious caesarean complications and are associated with elevated health care costs and maternal morbidity[2] Another factor that emphasizes the clinical significance of such infections is the rising worldwide rates of caesarean deliveries[3]; this growing rate predicts a parallel increase in caesarean surgical site infection cases. Total infections were detected during the initial hospital stay[10], while the rest were detected following discharge during the 30 postoperative days This result pinpoints the importance of post-discharge surveillance systems in identifying SSI cases. This study aimed to identify factors associated with an increased risk of SSIs
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
