Abstract
ObjectivesTo determine the prevalence of surgical site infections (SSIs) in neonatal congenital heart disease patients undergoing delayed sternal closure (DSC) and evaluate risk factors for SSI.MethodsHospital records of 483 consecutive neonates who underwent surgical intervention between January 2013 and December 2017 were reviewed, and perioperative variables were recorded.ResultsWe found that the prevalence of SSI was 87.5% when the body weight was less than 1500 g. When the operative age was between seven and 14 days, the probability of no SSI is about 93.9%. When the duration of the aortic cross-clamp was more than 60 min, the prevalence of SSI was 91.2%. The prevalence without SSI was 96.6% when the duration of DSC was less than 24 h. However, when the duration of DSC was more than 120 h, the prevalence of SSI was 88.9% (p = 0.000).ConclusionsWith the prolongation of aortic clamping duration, the probability of occurrence of SSI increased in neonatal CHD with DSC. The age at operation and body weight are closely related to the occurrence of SSI in neonatal CHD patients with DSC.
Highlights
The field of pediatric and neonatal cardiac surgery has witnessed major advances in the past 30 years [1]
In research on preoperative factors, we found that the prevalence of Surgical site infections (SSIs) was 87.5% when the body weight was less than 1500 g
We found that the probability of SSI was 84.6% when the operative age was less than 1 day and 84% when the operative age was less than 3 days
Summary
The field of pediatric and neonatal cardiac surgery has witnessed major advances in the past 30 years [1]. Most centers in China have reported excellent outcomes for neonatal cardiac surgery. Postoperative health care–associated infections after pediatric cardiac surgery remain significant causes of morbidity and mortality [3,4,5,6]. Yang et al Italian Journal of Pediatrics (2021) 47:182 patient population, there is limited data describing the epidemiology, prevalence factors, and patient outcomes and for those patients, this data may provide prognostic information, inform strategies for prevalence factors, and guide diagnostic workup and empiric antimicrobial therapy; c) The potential causative factors for SSI in this patient population have been as yet incompletely explored or characterized [15]. A clear understanding of outcomes and risk factors is essential because they may affect clinical decision making by cardiac surgeons and intensivists caring for these patients
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