Abstract

Thirty-two cases of metastatic brain tumor from lung cancer were retrospectively analyzed. Median survival time after the treatment of metastatic brain tumor was 29 weeks (7 months), with the longest survival being 10 years. Factors such as surgical removal of the metastatic brain tumor, radiation therapy for the brain, and Karnofsky performance status of more than 80 were shown to be associated with significantly improved survival. Meningeal carcinomatosis was associated with poorer survival. Gender, age, single or multiple metastasis, histological type and chemotherapy were not associated with prognosis. Nine autopsy cases showed that the cause of death was mainly brain metastasis in two cases, and mainly progression of lung cancer with cachexia in 7 cases. For better treatment, cooperation among oncologists, radiologists, radiation oncologists, surgeons, neurosurgeons and psychiatrists must be improved.

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