Surgical outcome of vitrectomy for macular hole secondary to uveitis

Abstract

acular holes secondary to uve-itis are known to occur onlyextremely rarely and therefore fewcaseshavebeenreported(Angioi-Duprezet al. 2001; Kusaka et al. 2003; Georg-alas et al. 2008). Accordingly, the patho-genesis of uveitic macular hole formationand the most appropriate therapeuticmethods have not been established andtreatment outcomes are unclear. Wedescribe a case series of macular holessecondary to uveitis, all of which weresuccessfully closed with vitrectomy.The medical records of patients withuveitis who underwent vitrectomy at asingle tertiary hospital between Janu-ary 1998 and December 2007 were ret-rospectively reviewed. The inclusioncriteria applied were as follows: thedevelopment of a macular hole wasdirectly related to the underlying uve-itis and not to trauma or to any othersecondary cause, such as myopic macu-lar degeneration, and the uveitisinvolved the vitreous or posterior ret-ina, such as in intermediate, posterioror panuveitis. Macular holes were con-firmed by the internal drainage of sub-retinal fluid during vitrectomy or thepresence of a definite full-thicknessmacular hole in intraoperative view oron optical coherence tomography.Seven consecutive cases (five men,two women; mean age 46 ± 13 years),