Surgical Operation as Stress and its Influence on Electrophoretic Pattern of Blood Plasma Proteins

Abstract

Changes in electrophoretic pattern of plasma proteins were studied in 11 cases of thracoplastik operations from the standpoint of regarding surgical operation as a stress. In addition, some indexes for adaptation responses (Ogawa's colloid reaction, Urinary glucose-total-reduction-power-ratio, etc.), changes of peripheral blood pictures, nitrogen excretion, and nitrogen balance were also studied.The changes in plasma proteins were classified into the following three groups;A: in which A/G was normal before operation, whereas decrease in Alb. and increase in total Glob. was obserdev after surgical operation.B: in which A/G was very low before operation, whereas increase in Alb. and decrease in total Glob. was observed after operation.C: in which A/G was low before operation, whereas decrease in both Alb. and total Glob. was observed after operation.In all cases, however, it was noted that the percentage of γ-Glob-fraction was definitely lowered, suggesting a_ catabolic effect by the surgical operation. These changes became maximum at the third day following the operation, when the changes in peripheral blood picture and all indexes of adaptation responses were already on the road of recovery while the urinary excretion of nitrogen and the negative nitrogen balance were at the highest levels.