Surgical newborns and the intestinal microbiome colonization: Dysbiotic relationship

Abstract

Rationale: Intestinal microbiota in the neonate is highly susceptible to perturbations of the luminal environment. Severe newborn infants admitted to Neonatal Intensive Care Units (NICUs), especially those with gastrointestinal (GI) complications, are even more susceptible to environmental influences, which can lead to disorders of the intestinal microbiota and possible proliferation of pathogenic bacteria.