Abstract
To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analysis and the log rank test. The mean age was 60.78 years. Total vulvectomy was performed in all patients. Superficial and deep incision of bilateral inguinal lymphadenectomy was performed by separates incisions for SCC infiltrating more than 1mm. The average tumor size was 53 mm (10 to 140mm). Morbidity was 42.1%. Lateral resection margin ≥8mm was obtained in 57.1%. Eighteen patients benefited from adjuvant radiotherapy. The follow-up median was 19.4 months (6 to 61.5 month) with 05 recurrences in 12 months. The survival using the Kaplan-Meyer analysis at 5 years, was 62.1% (71.2%N- vs 46.7%N+; p = 0.13). We identified two groups for locally advanced vulva cancer. Primary surgery keeps its place. Neo adjuvant radio chemotherapy followed by surgery is the alternative treatment for locally extensive lesions.
Highlights
To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva
In the light of literature data, we present our series of 38 cases of vulvar SCC, discuss our result and therapeutic indications especially in locally advanced stages which management is not yet codified
Anatomo-pathological results of biopsy samples made before surgery revealed 36 cases of infiltrating SCC and 02 cases of in situ lesions extended to the vulvar
Summary
To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Introduction quamous cell carcinoma (SCC) of vulva is a rare cancer. It represents 3-5% of gynecological cancers with an incidence of 2 per 100 000 women/year [1]. The treatment is well codified for the early stages whereas locally advanced carcinomas (stage III and IV) may be difficult to manage. The morbidity of this inguinal vulvar surgery may be important. Radiotherapy and/or chemotherapy progressively find more important place in the treatment of localized SCC of vulva. In the light of literature data, we present our series of 38 cases of vulvar SCC, discuss our result and therapeutic indications especially in locally advanced stages which management is not yet codified
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